Production of Recombinant Replication-defective Lentiviruses Bearing the SARS-CoV or SARS-CoV-2 Attachment Spike Glycoprotein and Their Application in Receptor Tropism and Neutralisation Assays

For enveloped viruses, such as SARS-CoV-2, transmission relies on the binding of viral glycoproteins to cellular receptors. Conventionally, this process is recapitulated in the lab by infection of cells with isolated live virus. However, such studies can be restricted due to the availability of high...

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Detalles Bibliográficos
Autores principales: Thakur, Nazia, Gallo, Giulia, Elreafey, Ahmed M. E., Bailey, Dalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2021
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595443/
https://www.ncbi.nlm.nih.gov/pubmed/34859135
http://dx.doi.org/10.21769/BioProtoc.4249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595443/
https://www.ncbi.nlm.nih.gov/pubmed/34859135
http://dx.doi.org/10.21769/BioProtoc.4249

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