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Generation of an NFκB-Driven Alpharetroviral “All-in-One” Vector Construct as a Potent Tool for CAR NK Cell Therapy

Immune cell therapeutics are increasingly applied in oncology. Especially chimeric antigen receptor (CAR) T cells are successfully used to treat several B cell malignancies. Efforts to engineer CAR T cells for improved activity against solid tumors include co-delivery of pro-inflammatory cytokines i...

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Detalles Bibliográficos
Autores principales: Rudek, Loreen Sophie, Zimmermann, Katharina, Galla, Melanie, Meyer, Johann, Kuehle, Johannes, Stamopoulou, Andriana, Brand, Daniel, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Rossig, Claudia, Altvater, Bianca, Falk, Christine S., Abken, Hinrich, Morgan, Michael Alexander, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595471/
https://www.ncbi.nlm.nih.gov/pubmed/34804035
http://dx.doi.org/10.3389/fimmu.2021.751138