Cargando…

Stability and conformation of the dimeric HIV-1 genomic RNA 5′UTR

During HIV-1 assembly, the viral Gag polyprotein specifically selects the dimeric RNA genome for packaging into new virions. The 5′ untranslated region (5′UTR) of the dimeric genome may adopt a conformation that is optimal for recognition by Gag. Further conformational rearrangement of the 5′UTR, pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Blakemore, Robert J., Burnett, Cleo, Swanson, Canessa, Kharytonchyk, Siarhei, Telesnitsky, Alice, Munro, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595565/
https://www.ncbi.nlm.nih.gov/pubmed/34529947
http://dx.doi.org/10.1016/j.bpj.2021.09.017