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Stability and conformation of the dimeric HIV-1 genomic RNA 5′UTR
During HIV-1 assembly, the viral Gag polyprotein specifically selects the dimeric RNA genome for packaging into new virions. The 5′ untranslated region (5′UTR) of the dimeric genome may adopt a conformation that is optimal for recognition by Gag. Further conformational rearrangement of the 5′UTR, pr...
Autores principales: | Blakemore, Robert J., Burnett, Cleo, Swanson, Canessa, Kharytonchyk, Siarhei, Telesnitsky, Alice, Munro, James B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595565/ https://www.ncbi.nlm.nih.gov/pubmed/34529947 http://dx.doi.org/10.1016/j.bpj.2021.09.017 |
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