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Two New Dihydrosphingosine Analogs Against Mycobacterium tuberculosis Affect gltA1, lprQ, and rpsO Expression

The emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis strains threaten the control of tuberculosis. New antitubercular dihydrosphingosine analogs, named UCIs, have been evaluated in preclinical studies but their cellular and molecular mechanisms of action against M. tuberculosis are...

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Detalles Bibliográficos
Autores principales: Peñuelas-Urquides, Katia, Bermúdez de León, Mario, Silva-Ramírez, Beatriz, Castorena-Torres, Fabiola, Molina-Salinas, Gloria María, Castro-Garza, Jorge, Becerril-Montes, Pola, del Olmo, Esther, San Feliciano, Arturo, González-Escalante, Laura Adiene, Villarreal-Treviño, Licet, Said-Fernández, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595602/
https://www.ncbi.nlm.nih.gov/pubmed/34803964
http://dx.doi.org/10.3389/fmicb.2021.742867