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The Aurora B gradient sustains kinetochore stability in anaphase

Kinetochores assemble on chromosomes in mitosis to allow microtubules to attach and bring about accurate chromosome segregation. The kinases Cyclin B-Cdk1 and Aurora B are crucial for the formation of stable kinetochores. However, the activity of these two kinases appears to decline dramatically at...

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Detalles Bibliográficos
Autores principales: Papini, Diana, Levasseur, Mark D., Higgins, Jonathan M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595645/
https://www.ncbi.nlm.nih.gov/pubmed/34758321
http://dx.doi.org/10.1016/j.celrep.2021.109818