Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing

During chemotaxis, neutrophils use cell surface G Protein Coupled Receptors to detect chemoattractant gradients. The downstream signaling system is wired with multiple feedback loops that amplify weak inputs and promote spatial separation of cell front and rear activities. Positive feedback could pr...

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Detalles Bibliográficos
Autores principales: Bell, George R. R., Rincón, Esther, Akdoğan, Emel, Collins, Sean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595684/
https://www.ncbi.nlm.nih.gov/pubmed/34785668
http://dx.doi.org/10.1038/s41467-021-26371-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595684/
https://www.ncbi.nlm.nih.gov/pubmed/34785668
http://dx.doi.org/10.1038/s41467-021-26371-z

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