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Apoptosis-associated speck-like protein containing a CARD regulates the growth of pancreatic ductal adenocarcinoma

Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is a key adaptor protein of inflammasomes and a proapoptotic molecule; however, its roles in signal transduction in pancreatic ductal adenocarcinoma (PDAC) cells remain unknown. Here, we clarified the role and mech...

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Detalles Bibliográficos
Autores principales: Koizumi, Mitsuhito, Watanabe, Takao, Masumoto, Junya, Sunago, Kotaro, Imamura, Yoshiki, Kanemitsu, Kozue, Kumagi, Teru, Hiasa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595714/
https://www.ncbi.nlm.nih.gov/pubmed/34785680
http://dx.doi.org/10.1038/s41598-021-01465-2