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Probing multiple enzymatic methylation events in real time with NMR spectroscopy

Post-translational modification (PTM) of proteins is of critical importance to the regulation of many cellular processes in eukaryotic organisms. One of the most well-studied protein PTMs is methylation, wherein an enzyme catalyzes the transfer of a methyl group from a cofactor to a lysine or argini...

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Detalles Bibliográficos
Autores principales: Usher, Emery T., Namitz, Kevin E.W., Cosgrove, Michael S., Showalter, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595733/
https://www.ncbi.nlm.nih.gov/pubmed/34592262
http://dx.doi.org/10.1016/j.bpj.2021.09.034