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Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate

Organophosphate (OP) nerve agents and pesticides are a class of neurotoxic compounds that can cause status epilepticus (SE), and death following acute high-dose exposures. While the standard of care for acute OP intoxication (atropine, oxime, and high-dose benzodiazepine) can prevent mortality, surv...

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Detalles Bibliográficos
Autores principales: Calsbeek, Jonas J., González, Eduardo A., Bruun, Donald A., Guignet, Michelle A., Copping, Nycole, Dawson, Mallory E., Yu, Alexandria J., MacMahon, Jeremy A., Saito, Naomi H., Harvey, Danielle J., Silverman, Jill L., Lein, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595753/
https://www.ncbi.nlm.nih.gov/pubmed/34509511
http://dx.doi.org/10.1016/j.neuro.2021.09.001