Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients

Hepatocyte growth factor-overexpressing mice that harbor a deletion of the Ink4a/p16 locus (HP mice) form melanomas with low metastatic potential in response to UV irradiation. Here we report that these tumors become highly metastatic following hemizygous deletion of the Nme1 and Nme2 metastasis sup...

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Detalles Bibliográficos
Autores principales: Leonard, M. Kathryn, Puts, Gemma S., Pamidimukkala, Nidhi, Adhikary, Gautam, Xu, Yili, Kwok, Eric, Jin, Yuxin, Snyder, Devin, Matsangos, Nicolette, Novak, Marián, Mahurkar, Anup, Shetty, Amol C., Slominski, Radomir M., De Fabo, Edward C., Noonan, Frances P., Day, Chi-Ping, Rigi, Mohammed, Slominski, Andrzej T., Webb, Michelle G., Craig, David W., Merlino, Glenn, Eckert, Richard L., Carpten, John D., Manojlovic, Zarko, Kaetzel, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595820/
https://www.ncbi.nlm.nih.gov/pubmed/34433909
http://dx.doi.org/10.1038/s41388-021-01998-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595820/
https://www.ncbi.nlm.nih.gov/pubmed/34433909
http://dx.doi.org/10.1038/s41388-021-01998-w

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