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Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome

Obesity leads to ovarian dysfunction and the establishment of local leptin resistance. The aim of our study was to characterize the levels of NOD-like receptor protein 3 (NLRP3) inflammasome activation in ovaries and liver of mice during obesity progression. Furthermore, we tested the putative role...

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Detalles Bibliográficos
Autores principales: Adamowski, Marek, Wołodko, Karolina, Oliveira, Joana, Castillo-Fernandez, Juan, Murta, Daniel, Kelsey, Gavin, Galvão, António M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595835/
https://www.ncbi.nlm.nih.gov/pubmed/34805147
http://dx.doi.org/10.3389/fcell.2021.738731