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Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome
Obesity leads to ovarian dysfunction and the establishment of local leptin resistance. The aim of our study was to characterize the levels of NOD-like receptor protein 3 (NLRP3) inflammasome activation in ovaries and liver of mice during obesity progression. Furthermore, we tested the putative role...
Autores principales: | Adamowski, Marek, Wołodko, Karolina, Oliveira, Joana, Castillo-Fernandez, Juan, Murta, Daniel, Kelsey, Gavin, Galvão, António M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595835/ https://www.ncbi.nlm.nih.gov/pubmed/34805147 http://dx.doi.org/10.3389/fcell.2021.738731 |
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