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Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens
Bacterial human pathogens secrete initially inactive nucleotidyl cyclases that become potent enzymes by binding to actin inside eukaryotic host cells. The underlying molecular mechanism of this activation is, however, unclear. Here, we report structures of ExoY from Pseudomonas aeruginosa and Vibrio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595890/ https://www.ncbi.nlm.nih.gov/pubmed/34785651 http://dx.doi.org/10.1038/s41467-021-26889-2 |