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Lipopolysaccharide-induced neuroinflammation disrupts functional connectivity and community structure in primary cortical microtissues

Three-dimensional (3D) neural microtissues are a powerful in vitro paradigm for studying brain development and disease under controlled conditions, while maintaining many key attributes of the in vivo environment. Here, we used primary cortical microtissues to study the effects of neuroinflammation...

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Detalles Bibliográficos
Autores principales: Atherton, Elaina, Brown, Sophie, Papiez, Emily, Restrepo, Maria I., Borton, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595892/
https://www.ncbi.nlm.nih.gov/pubmed/34785714
http://dx.doi.org/10.1038/s41598-021-01616-5