Highly Diastereoselective Synthesis of Tetrahydroquinoline Derivatives via [4 + 2] Annulation of Ortho-Tosylaminophenyl-Substituted Para-Quinone Methides and Cyanoalkenes

As a privileged structural motif, tetrahydroquinoline skeletons widely exist in biologically active natural products and pharmaceuticals. In this protocol, a highly diastereoselective [4 + 2] annulation of ortho-tosylaminophenyl-substituted p-QMs and cyanoalkenes to construct tetrahydroquinoline der...

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Detalles Bibliográficos
Autores principales: Dong, Taiwei, Wei, Peifeng, Li, Min, Gao, Feng, Qin, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595915/
https://www.ncbi.nlm.nih.gov/pubmed/34805095
http://dx.doi.org/10.3389/fchem.2021.764866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595915/
https://www.ncbi.nlm.nih.gov/pubmed/34805095
http://dx.doi.org/10.3389/fchem.2021.764866

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