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Newcastle disease vaccine virus I-2 fails to acquire virulence during repeated passage in vivo

Background This study determined whether the naturally attenuated, thermotolerant Newcastle disease vaccine virus I-2 could acquire virulence after five in vivo passages through SPF chickens. Methods Study design was to international requirements including European Pharmacopoeia, Ph. Eur., v9.0 04/2...

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Detalles Bibliográficos
Autores principales: Bisschop, Shahn P.R., Peters, Andrew, Domingue, Gil, Pearce, Michael C., Verwey, Jeanette, Poolman, Petrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595976/
https://www.ncbi.nlm.nih.gov/pubmed/34859194
http://dx.doi.org/10.12688/gatesopenres.13212.3