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Newcastle disease vaccine virus I-2 fails to acquire virulence during repeated passage in vivo
Background This study determined whether the naturally attenuated, thermotolerant Newcastle disease vaccine virus I-2 could acquire virulence after five in vivo passages through SPF chickens. Methods Study design was to international requirements including European Pharmacopoeia, Ph. Eur., v9.0 04/2...
Autores principales: | Bisschop, Shahn P.R., Peters, Andrew, Domingue, Gil, Pearce, Michael C., Verwey, Jeanette, Poolman, Petrus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595976/ https://www.ncbi.nlm.nih.gov/pubmed/34859194 http://dx.doi.org/10.12688/gatesopenres.13212.3 |
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