Cytoplasmic NEAT1 Suppresses AML Stem Cell Self‐Renewal and Leukemogenesis through Inactivation of Wnt Signaling

As an essential component of paraspeckles, nuclear paraspeckle assembly transcript 1 (NEAT1) localizes in the nucleus, promoting progression of various malignant solid tumors. Herein, an adverse effect of NEAT1 is reported, showing that the short isoform, NEAT1_1 suppresses acute myeloid leukemia (A...

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Detalles Bibliográficos
Autores principales: Yan, Huiwen, Wang, Zhi, Sun, Yao, Hu, Liangding, Bu, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596104/
https://www.ncbi.nlm.nih.gov/pubmed/34609794
http://dx.doi.org/10.1002/advs.202100914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596104/
https://www.ncbi.nlm.nih.gov/pubmed/34609794
http://dx.doi.org/10.1002/advs.202100914

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