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Cytoplasmic NEAT1 Suppresses AML Stem Cell Self‐Renewal and Leukemogenesis through Inactivation of Wnt Signaling

As an essential component of paraspeckles, nuclear paraspeckle assembly transcript 1 (NEAT1) localizes in the nucleus, promoting progression of various malignant solid tumors. Herein, an adverse effect of NEAT1 is reported, showing that the short isoform, NEAT1_1 suppresses acute myeloid leukemia (A...

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Detalles Bibliográficos
Autores principales:	Yan, Huiwen, Wang, Zhi, Sun, Yao, Hu, Liangding, Bu, Pengcheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596104/ https://www.ncbi.nlm.nih.gov/pubmed/34609794 http://dx.doi.org/10.1002/advs.202100914

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