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Rational Design of a Modality‐Specific Inhibitor of TRPM8 Channel against Oxaliplatin‐Induced Cold Allodynia

Platinum‐based compounds in chemotherapy such as oxaliplatin often induce peripheral neuropathy and neuropathic pain such as cold allodynia in patients. Transient Receptor Potential Melastatin 8 (TRPM8) ion channel is a nociceptor critically involved in such pathological processes. Direct blockade o...

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Detalles Bibliográficos
Autores principales: Aierken, Aerziguli, Xie, Ya‐Kai, Dong, Wenqi, Apaer, Abuliken, Lin, Jia‐Jia, Zhao, Zihan, Yang, Shilong, Xu, Zhen‐Zhong, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596132/
https://www.ncbi.nlm.nih.gov/pubmed/34658162
http://dx.doi.org/10.1002/advs.202101717