Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder

Background and Purpose: Mitragyna speciosa extract and kratom alkaloids decrease alcohol consumption in mice at least in part through actions at the δ-opioid receptor (δOR). However, the most potent opioidergic kratom alkaloid, 7-hydroxymitragynine, exhibits rewarding properties and hyperlocomotion...

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Detalles Bibliográficos
Autores principales: Gutridge, Anna M., Chakraborty, Soumen, Varga, Balazs R., Rhoda, Elizabeth S., French, Alexander R., Blaine, Arryn T., Royer, Quinten H., Cui, Haoyue, Yuan, Jinling, Cassell, Robert J., Szabó, Márk, Majumdar, Susruta, van Rijn, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596301/
https://www.ncbi.nlm.nih.gov/pubmed/34803709
http://dx.doi.org/10.3389/fphar.2021.764885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596301/
https://www.ncbi.nlm.nih.gov/pubmed/34803709
http://dx.doi.org/10.3389/fphar.2021.764885

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