N(6)-methyladenine in DNA antagonizes SATB1 in early development

The recent discovery of N(6)-mA in mammalian genomes suggests that it may serve as an epigenetic regulatory mechanism(1). However, the biological role of N(6)-mA and molecular pathways exerting its function remain elusive. Herein, we demonstrate that N(6)-mA plays a critical role in changing the epi...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Zhao, Shuai, Nelakanti, Raman V., Lin, Kaixuan, Wu, Tao P., Alderman, Myles H., Guo, Cheng, Wang, Pengcheng, Zhang, Min, Min, Wang, Jiang, Zongliang, Wang, Yinsheng, Li, Haitao, Xiao, Andrew Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596487/
https://www.ncbi.nlm.nih.gov/pubmed/32669713
http://dx.doi.org/10.1038/s41586-020-2500-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596487/
https://www.ncbi.nlm.nih.gov/pubmed/32669713
http://dx.doi.org/10.1038/s41586-020-2500-9

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