Catalytic Enantioselective Access to Dihydroquinoxalinones via Formal α‐Halo Acyl Halide Synthon in One Pot

An enantioselective one‐pot catalytic strategy to dihydroquinoxalinones, featuring novel 1‐phenylsulfonyl‐1‐cyano enantioenriched epoxides as masked α‐halo acyl halide synthons, followed by a domino ring‐opening cyclization (DROC), is documented. A popular quinine‐derived urea served as the catalyst...

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Detalles Bibliográficos
Autores principales: Volpe, Chiara, Meninno, Sara, Crescenzi, Carlo, Mancinelli, Michele, Mazzanti, Andrea, Lattanzi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596509/
https://www.ncbi.nlm.nih.gov/pubmed/34437760
http://dx.doi.org/10.1002/anie.202110173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596509/
https://www.ncbi.nlm.nih.gov/pubmed/34437760
http://dx.doi.org/10.1002/anie.202110173

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