Full‐Atom Model of the Agonist LPS‐Bound Toll‐like Receptor 4 Dimer in a Membrane Environment

The Toll‐like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD‐2) innate immunity system is a membrane receptor of paramount importance as therapeutic target. Its assembly, upon binding of Gram‐negative bacteria lipopolysaccharide (LPS), and also dependent on the membrane composition, finally...

Descripción completa

Detalles Bibliográficos
Autores principales: Matamoros‐Recio, Alejandra, Franco‐Gonzalez, Juan Felipe, Perez‐Regidor, Lucia, Billod, Jean‐Marc, Guzman‐Caldentey, Joan, Martin‐Santamaria, Sonsoles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596573/
https://www.ncbi.nlm.nih.gov/pubmed/34569111
http://dx.doi.org/10.1002/chem.202102995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596573/
https://www.ncbi.nlm.nih.gov/pubmed/34569111
http://dx.doi.org/10.1002/chem.202102995

Ejemplares similares