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Full‐Atom Model of the Agonist LPS‐Bound Toll‐like Receptor 4 Dimer in a Membrane Environment

The Toll‐like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD‐2) innate immunity system is a membrane receptor of paramount importance as therapeutic target. Its assembly, upon binding of Gram‐negative bacteria lipopolysaccharide (LPS), and also dependent on the membrane composition, finally...

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Detalles Bibliográficos
Autores principales:	Matamoros‐Recio, Alejandra, Franco‐Gonzalez, Juan Felipe, Perez‐Regidor, Lucia, Billod, Jean‐Marc, Guzman‐Caldentey, Joan, Martin‐Santamaria, Sonsoles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596573/ https://www.ncbi.nlm.nih.gov/pubmed/34569111 http://dx.doi.org/10.1002/chem.202102995

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