Biocatalytic C3‐Indole Methylation—A Useful Tool for the Natural‐Product‐Inspired Stereoselective Synthesis of Pyrroloindoles

Enantioselective synthesis of bioactive compounds bearing a pyrroloindole framework is often laborious. In contrast, there are several S‐adenosyl methionine (SAM)‐dependent methyl transferases known for stereo‐ and regioselective methylation at the C3 position of various indoles, directly leading to...

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Detalles Bibliográficos
Autores principales: Schneider, Pascal, Henßen, Birgit, Paschold, Beatrix, Chapple, Benjamin P., Schatton, Marcel, Seebeck, Florian P., Classen, Thomas, Pietruszka, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596708/
https://www.ncbi.nlm.nih.gov/pubmed/34399441
http://dx.doi.org/10.1002/anie.202107619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596708/
https://www.ncbi.nlm.nih.gov/pubmed/34399441
http://dx.doi.org/10.1002/anie.202107619

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