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Biocatalytic C3‐Indole Methylation—A Useful Tool for the Natural‐Product‐Inspired Stereoselective Synthesis of Pyrroloindoles
Enantioselective synthesis of bioactive compounds bearing a pyrroloindole framework is often laborious. In contrast, there are several S‐adenosyl methionine (SAM)‐dependent methyl transferases known for stereo‐ and regioselective methylation at the C3 position of various indoles, directly leading to...
Autores principales: | Schneider, Pascal, Henßen, Birgit, Paschold, Beatrix, Chapple, Benjamin P., Schatton, Marcel, Seebeck, Florian P., Classen, Thomas, Pietruszka, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596708/ https://www.ncbi.nlm.nih.gov/pubmed/34399441 http://dx.doi.org/10.1002/anie.202107619 |
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