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Biocatalytic Asymmetric Cyclopropanations via Enzyme‐Bound Iminium Ion Intermediates
Cyclopropane rings are an important structural motif frequently found in many natural products and pharmaceuticals. Commonly, biocatalytic methodologies for the asymmetric synthesis of cyclopropanes rely on repurposed or artificial heme enzymes. Here, we engineered an unusual cofactor‐independent cy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596749/ https://www.ncbi.nlm.nih.gov/pubmed/34490955 http://dx.doi.org/10.1002/anie.202110719 |