Population Pharmacokinetics of Olanzapine and Samidorphan When Administered in Combination in Healthy Subjects and Patients With Schizophrenia

A combination of olanzapine and samidorphan was recently approved by the US Food and Drug Administration for the treatment of patients with schizophrenia or bipolar I disorder. Population pharmacokinetic models for olanzapine and samidorphan were developed using data from 11 clinical studies in heal...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Mills, Richard, Sadler, Brian M., Rege, Bhaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Pharmacometrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596792/
https://www.ncbi.nlm.nih.gov/pubmed/34018607
http://dx.doi.org/10.1002/jcph.1911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596792/
https://www.ncbi.nlm.nih.gov/pubmed/34018607
http://dx.doi.org/10.1002/jcph.1911

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