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BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

Osteoporosis is a common aging-related metabolic disease that mainly occurs in older adults and postmenopausal women. Despite advances in anti-osteoporosis treatment, outcomes remain unsatisfactory due to detrimental side effects. BCI hydrochloride (BCI), a selective dual-specificity phosphatase 6 (...

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Detalles Bibliográficos
Autores principales: Cai, Chenhui, Hu, Wenhui, Zhang, Ying, Hu, Xu, Yang, Sizhen, Qiu, Hao, Wang, Rujie, Ma, Min, Qiu, Yiyun, Chu, Tongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596812/
https://www.ncbi.nlm.nih.gov/pubmed/34803714
http://dx.doi.org/10.3389/fphar.2021.772540