A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis

Our study aimed to explore the function of circRNA_0001805 in the pathogenesis of NAFLD and the underlying mechanism. A nanodrug system (GA-RM/GZ/PL) was constructed to overexpress circRNA_0001805 specifically in hepatocytes for the treatment of NAFLD. Fat droplet accumulation in cultured cells and...

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Detalles Bibliográficos
Autores principales: Li, Jian, Qi, Jing, Tang, Yishu, Liu, Huaizheng, Zhou, Kefu, Dai, Zheren, Yuan, Lehong, Sun, Chuanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596892/
https://www.ncbi.nlm.nih.gov/pubmed/34789275
http://dx.doi.org/10.1186/s12951-021-01108-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596892/
https://www.ncbi.nlm.nih.gov/pubmed/34789275
http://dx.doi.org/10.1186/s12951-021-01108-8

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