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A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis

Our study aimed to explore the function of circRNA_0001805 in the pathogenesis of NAFLD and the underlying mechanism. A nanodrug system (GA-RM/GZ/PL) was constructed to overexpress circRNA_0001805 specifically in hepatocytes for the treatment of NAFLD. Fat droplet accumulation in cultured cells and...

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Detalles Bibliográficos
Autores principales:	Li, Jian, Qi, Jing, Tang, Yishu, Liu, Huaizheng, Zhou, Kefu, Dai, Zheren, Yuan, Lehong, Sun, Chuanzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596892/ https://www.ncbi.nlm.nih.gov/pubmed/34789275 http://dx.doi.org/10.1186/s12951-021-01108-8

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