TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway

BACKGROUND: Glaucoma, the leading cause of irreversible blindness worldwide, is a type of retinal disease characterized by the selective death of retinal ganglion cells (RGCs). However, the pathogenesis of glaucoma has not been fully elucidated. Transient receptor potential vanilloid 4 (TRPV4) is a...

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Detalles Bibliográficos
Autores principales: Li, Qian, Cheng, Yun, Zhang, Shenghai, Sun, Xinghuai, Wu, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596927/
https://www.ncbi.nlm.nih.gov/pubmed/34789280
http://dx.doi.org/10.1186/s12974-021-02315-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596927/
https://www.ncbi.nlm.nih.gov/pubmed/34789280
http://dx.doi.org/10.1186/s12974-021-02315-8

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