Unraveling a Ligand‐Induced Twist of a Homodimeric Enzyme by Pulsed Electron–Electron Double Resonance

Mechanistic insights into protein–ligand interactions can yield chemical tools for modulating protein function and enable their use for therapeutic purposes. For the homodimeric enzyme tRNA‐guanine transglycosylase (TGT), a putative virulence target of shigellosis, ligand binding has been shown by c...

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Detalles Bibliográficos
Autores principales: Nguyen, Dzung, Abdullin, Dinar, Heubach, Caspar A., Pfaffeneder, Toni, Nguyen, Andreas, Heine, Andreas, Reuter, Klaus, Diederich, François, Schiemann, Olav, Klebe, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597004/
https://www.ncbi.nlm.nih.gov/pubmed/34387025
http://dx.doi.org/10.1002/anie.202108179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597004/
https://www.ncbi.nlm.nih.gov/pubmed/34387025
http://dx.doi.org/10.1002/anie.202108179

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