Cargando…

Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label‐Free Assessment of Cell Permeability

The major obstacle in applying peptides to intracellular targets is their low inherent cell permeability. Standard approaches to attach a fluorophore (e. g. FITC, TAMRA) can change the physicochemical properties of the parent peptide and influence their ability to penetrate and localize in cells. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yuteng, Bertran, M. Teresa, Rowley, James, Calder, Ewen D. D., Joshi, Dhira, Walport, Louise J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597039/
https://www.ncbi.nlm.nih.gov/pubmed/34236771
http://dx.doi.org/10.1002/cmdc.202100315