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Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response

The effects of ER stress on protein secretion by cardiac myocytes are not well understood. In this study, the ER stressor thapsigargin (TG), which depletes ER calcium, induced death of cultured neonatal rat ventricular myocytes (NRVMs) in high media volume but fostered protection in low media volume...

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Detalles Bibliográficos
Autores principales: Blackwood, Erik A., Thuerauf, Donna J., Stastna, Miroslava, Stephens, Haley, Sand, Zoe, Pentoney, Amber, Azizi, Khalid, Jakobi, Tobias, Van Eyk, Jennifer E., Katus, Hugo A., Glembotski, Christopher C., Doroudgar, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597053/
https://www.ncbi.nlm.nih.gov/pubmed/32339566
http://dx.doi.org/10.1016/j.yjmcc.2020.04.012