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Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response
The effects of ER stress on protein secretion by cardiac myocytes are not well understood. In this study, the ER stressor thapsigargin (TG), which depletes ER calcium, induced death of cultured neonatal rat ventricular myocytes (NRVMs) in high media volume but fostered protection in low media volume...
Autores principales: | Blackwood, Erik A., Thuerauf, Donna J., Stastna, Miroslava, Stephens, Haley, Sand, Zoe, Pentoney, Amber, Azizi, Khalid, Jakobi, Tobias, Van Eyk, Jennifer E., Katus, Hugo A., Glembotski, Christopher C., Doroudgar, Shirin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597053/ https://www.ncbi.nlm.nih.gov/pubmed/32339566 http://dx.doi.org/10.1016/j.yjmcc.2020.04.012 |
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