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Strategies to Avoid Artifacts in Mass Spectrometry‐Based Epitranscriptome Analyses

In this report, we perform structure validation of recently reported RNA phosphorothioate (PT) modifications, a new set of epitranscriptome marks found in bacteria and eukaryotes including humans. By comparing synthetic PT‐containing diribonucleotides with native species in RNA hydrolysates by high‐...

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Detalles Bibliográficos
Autores principales: Kaiser, Steffen, Byrne, Shane R., Ammann, Gregor, Asadi Atoi, Paria, Borland, Kayla, Brecheisen, Roland, DeMott, Michael S., Gehrke, Tim, Hagelskamp, Felix, Heiss, Matthias, Yoluç, Yasemin, Liu, Lili, Zhang, Qinghua, Dedon, Peter C., Cao, Bo, Kellner, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597057/
https://www.ncbi.nlm.nih.gov/pubmed/34339593
http://dx.doi.org/10.1002/anie.202106215