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New insights into the activities and toxicities of the old anticancer drug doxorubicin

The anthracycline drug doxorubicin is among the most used—and useful—chemotherapeutics. While doxorubicin is highly effective in the treatment of various hematopoietic malignancies and solid tumours, its application is limited by severe adverse effects, including irreversible cardiotoxicity, therapy...

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Detalles Bibliográficos
Autores principales: van der Zanden, Sabina Y., Qiao, Xiaohang, Neefjes, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597086/
https://www.ncbi.nlm.nih.gov/pubmed/33022843
http://dx.doi.org/10.1111/febs.15583