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Impact of Paroxetine, a Strong CYP2D6 Inhibitor, on SPN‐812 (Viloxazine Extended‐Release) Pharmacokinetics in Healthy Adults

SPN‐812 (viloxazine extended‐release) is a novel nonstimulant recently approved as a treatment for attention‐deficit/hyperactivity disorder in children and adolescents. Given that SPN‐812 is metabolized by CYP2D6 and may be coadministered with CYP2D6 inhibitors, this trial investigated the pharmacok...

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Detalles Bibliográficos
Autores principales: Wang, Zhao, Kosheleff, Alisa R., Adeojo, Lilian W., Odebo, Oyinkansola, Adewole, Toyin, Qin, Peibing, Maletic, Vladimir, Schwabe, Stefan, Nasser, Azmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597116/
https://www.ncbi.nlm.nih.gov/pubmed/33943033
http://dx.doi.org/10.1002/cpdd.948