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Chalcone‐Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering

Human pluripotent stem cells (hPSCs) hold great promise for applications in cell therapy and drug screening in the cardiovascular field. Bone morphogenetic protein 4 (BMP4) is key for early cardiac mesoderm induction in hPSC and subsequent cardiomyocyte derivation. Small‐molecular BMP4 mimetics may...

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Detalles Bibliográficos
Autores principales: Raad, Farah S., Khan, Taukeer A., Esser, Tilman U., Hudson, James E., Seth, Bhakti Irene, Fujita, Buntaro, Gandamala, Ravi, Tietze, Lutz F., Zimmermann, Wolfram-Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597156/
https://www.ncbi.nlm.nih.gov/pubmed/34309224
http://dx.doi.org/10.1002/cmdc.202100222