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The impact of chronic mild hypoxia on cerebrovascular remodelling; uncoupling of angiogenesis and vascular breakdown

BACKGROUND: Chronic mild hypoxia (CMH, 8% O(2)) stimulates robust vascular remodelling in the brain, but it also triggers transient vascular disruption. This raises the fundamental question: is the vascular leak an unwanted side-effect of angiogenic remodelling or is it a pathological response, unre...

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Detalles Bibliográficos
Autores principales: Halder, Sebok K., Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597176/
https://www.ncbi.nlm.nih.gov/pubmed/34789271
http://dx.doi.org/10.1186/s12987-021-00284-x