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Anticancer effects of mifepristone on human uveal melanoma cells

BACKGROUND: Uveal melanoma (UM), the most prevalent intraocular tumor in adults, is a highly metastatic and drug resistant lesion. Recent studies have demonstrated cytotoxic and anti-metastatic effects of the antiprogestin and antiglucocorticoid mifepristone (MF) in vitro and in clinical trials invo...

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Detalles Bibliográficos
Autores principales: Alvarez, Prisca Bustamante, Laskaris, Alexander, Goyeneche, Alicia A., Chen, Yunxi, Telleria, Carlos M., Burnier, Julia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597220/
https://www.ncbi.nlm.nih.gov/pubmed/34789240
http://dx.doi.org/10.1186/s12935-021-02306-y