Artificial exosomes mediated spatiotemporal-resolved and targeted delivery of epigenetic inhibitors

BACKGROUND: Malignant tumor is usually associated with epigenetic dysregulation, such as overexpression of histone deacetylase (HDAC), thus HDAC has emerged as a therapeutic target for cancer. Histone deacetylase inhibitor has been approved for clinical use to treat hematological cancers. However, t...

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Detalles Bibliográficos
Autores principales: Li, Huan, Li, Songpei, Lin, Yinshan, Chen, Sheng, Yang, Langyu, Huang, Xin, Wang, Hao, Yu, Xiyong, Zhang, Lingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597284/
https://www.ncbi.nlm.nih.gov/pubmed/34789273
http://dx.doi.org/10.1186/s12951-021-01107-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597284/
https://www.ncbi.nlm.nih.gov/pubmed/34789273
http://dx.doi.org/10.1186/s12951-021-01107-9

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