CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens

BACKGROUND: CRISPR-Cas9 genome-wide screens are being increasingly performed, allowing systematic explorations of cancer dependencies at unprecedented accuracy and scale. One of the major computational challenges when analysing data derived from such screens is to identify genes that are essential f...

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Detalles Bibliográficos
Autores principales: Vinceti, Alessandro, Karakoc, Emre, Pacini, Clare, Perron, Umberto, De Lucia, Riccardo Roberto, Garnett, Mathew J., Iorio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597285/
https://www.ncbi.nlm.nih.gov/pubmed/34789150
http://dx.doi.org/10.1186/s12864-021-08129-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597285/
https://www.ncbi.nlm.nih.gov/pubmed/34789150
http://dx.doi.org/10.1186/s12864-021-08129-5

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