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Formation of nuclear condensates by the Mediator complex subunit Med15 in mammalian cells

BACKGROUND: The Mediator complex is an evolutionarily conserved multi-subunit protein complex that plays major roles in transcriptional activation and is essential for cell growth, proliferation, and differentiation. Recent studies revealed that some Mediator subunits formed nuclear condensates that...

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Detalles Bibliográficos
Autores principales: Shi, Yuanyuan, Chen, Jian, Zeng, Wei-Jie, Li, Miao, Zhao, Wenxue, Zhang, Xing-Ding, Yao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597291/
https://www.ncbi.nlm.nih.gov/pubmed/34789250
http://dx.doi.org/10.1186/s12915-021-01178-y