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Formation of nuclear condensates by the Mediator complex subunit Med15 in mammalian cells
BACKGROUND: The Mediator complex is an evolutionarily conserved multi-subunit protein complex that plays major roles in transcriptional activation and is essential for cell growth, proliferation, and differentiation. Recent studies revealed that some Mediator subunits formed nuclear condensates that...
Autores principales: | Shi, Yuanyuan, Chen, Jian, Zeng, Wei-Jie, Li, Miao, Zhao, Wenxue, Zhang, Xing-Ding, Yao, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597291/ https://www.ncbi.nlm.nih.gov/pubmed/34789250 http://dx.doi.org/10.1186/s12915-021-01178-y |
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