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New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective, early degeneration of motor neurons in the brain and spinal cord. Motor neurons have long axonal projections, which rely on the integrity of neuronal cytoskeleton and mitochondria to regulate e...

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Detalles Bibliográficos
Autores principales: Theunissen, Frances, West, Phillip K., Brennan, Samuel, Petrović, Bojan, Hooshmand, Kosar, Akkari, P. Anthony, Keon, Matt, Guennewig, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597313/
https://www.ncbi.nlm.nih.gov/pubmed/34789332
http://dx.doi.org/10.1186/s40035-021-00272-z