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New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective, early degeneration of motor neurons in the brain and spinal cord. Motor neurons have long axonal projections, which rely on the integrity of neuronal cytoskeleton and mitochondria to regulate e...
Autores principales: | Theunissen, Frances, West, Phillip K., Brennan, Samuel, Petrović, Bojan, Hooshmand, Kosar, Akkari, P. Anthony, Keon, Matt, Guennewig, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597313/ https://www.ncbi.nlm.nih.gov/pubmed/34789332 http://dx.doi.org/10.1186/s40035-021-00272-z |
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